News

Ubiquitin marks abnormal glycogen for destruction to protect the brain

15 September 2026

Researchers at the University of Cambridge and the MRC Laboratory of Molecular Biology discovered how a cellular enzyme tags and clears toxic sugar in the brain, offering new targets for rare neurological diseases.

Gut infections can train the brain’s immune defences

8 September 2026

New study led by CITIID researchers at the University of Cambridge reveals that gut infections can influence immune responses in the brain and its protective lining, creating a long-lasting defence against life-threatening blood infections. Protected inside the solid bone of the skull, the brain is surrounded by a...

COVID-19 vaccine boosters may help protect against future animal coronaviruses

1 July 2026

Grace West, Rebecca Morse and other scientists in the Gupta and Rihn laboratories at CITIID has shown that an individual’s first exposure to SARS-CoV-2 ‘locks in’ their immune response, impeding their ability to respond to future variants, even when vaccinated.

Repurposed epilepsy drug could be used to boost vaccine protection among elderly

30 June 2026

Professor Eoin McKinney and colleagues showed that the drug more than doubled the number of antibodies against flu and increased 10‑fold the number of flu-specific CD8 T cells, a type of white blood cell that kills cells infected by flu.

John McCafferty: The antibody pioneer

27 May 2026

Newly elected both as a Fellow of the Academy of Medical Sciences and Fellow of the Royal Society, John McCafferty has spent more than 3 decades transforming antibodies from natural defenders into medicines that have improved millions of lives.

John McCafferty and James Nathan named as Fellows of 2026 Academy of Medical Sciences

21 May 2026

Professor John McCafferty and James Nathan have been recognised for their outstanding contributions to advancing medical science, each responsible for pioneering discovery research and translating innovation into tangible benefits for patients and the wider public. They join an esteemed Fellowship of over 1,500 researchers...

CITIID Research Highlight: David Jayne

14 May 2026

Our work aims to improve outcomes for patients with multi-system autoimmune disorders, particularly vasculitis, lupus and related conditions.

CITIID Research Highlight: Lalita Ramakrishnan

24 March 2026

Tuberculosis (TB) is an ancient infectious disease caused by bacteria, and it is by far the greatest infectious killer of humanity.

New vulnerability identified in common kidney cancer could open door to new treatments

17 March 2026

Published now in Nature Communications, the study led by James Bertlin, a CRUK-funded MBPhD student, and Professor James Nathan (CITIID) has uncovered a new target in the most common form of kidney cancer which offers a dual therapeutic benefit: selectively killing cancer cells while simultaneously activating the immune...

Professor Yorgo Modis leads collaborative project on MORC2-related disorder

24 February 2026

Professor Yorgo Modis (Department of Medicine, University of Cambridge) is leading a research project with MORCure , a patient-led global charity that leads research, innovation and best practice for individuals with MORC2-related disorder (M2RD), to generate new insights into how genetically inherited variants of the...

Ubiquitin marks abnormal glycogen for destruction to protect the brain

Gut infections can train the brain’s immune defences

COVID-19 vaccine boosters may help protect against future animal coronaviruses

Repurposed epilepsy drug could be used to boost vaccine protection among elderly

John McCafferty: The antibody pioneer

John McCafferty and James Nathan named as Fellows of 2026 Academy of Medical Sciences

CITIID Research Highlight: David Jayne

CITIID Research Highlight: Lalita Ramakrishnan

New vulnerability identified in common kidney cancer could open door to new treatments

Professor Yorgo Modis leads collaborative project on MORC2-related disorder

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